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From103US$ /night
Check-in
17Dec2025Select date
Check-out
18Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

9300 S Main Street, Houston, Texas, United States
-
Close to the Museum District
Great
8.9
9.3
/10
4.2
4.3
/5

Location

Holiday Inn Express & Suites Houston S - Medical Ctr Area is located one mile from NRG Stadium and Arena, providing easy access for sports and concert enthusiasts. The hotel offers a complimentary shuttle to the Texas Medical Center, making it convenient for medical travelers. Nearby attractions include the Houston Museum District and the NASA Johnson Space Center, both a short drive away.

Rooms

The hotel offers 146 newly designed guest rooms, available with one king bed or two queen beds. Each room includes standard amenities such as a 43-inch LCD HD TV, microwave, and mini refrigerator. Business travelers benefit from a work desk equipped with an ergonomic chair and high-speed internet access.

Dining

Guests can enjoy a complimentary hot breakfast each morning at the Express Start Breakfast Bar, featuring a variety of favorites. The hotel provides free coffee and tea supplies in the lobby for additional convenience. The nearby dining options also offer a broad range of culinary experiences, catering to diverse tastes.

Wellness

The hotel includes a fitness center, equipped with cardio machines and free weights, allowing guests to maintain their fitness routine. An outdoor pool provides a refreshing option for relaxation during warmer days, with accessibility from 10 AM to 10 PM. Both wellness areas contribute to a balanced and active stay.

Business

A business center is available for guests needing work-related services such as printing and copying. The hotel also has a large, dividable meeting room that accommodates up to 66 people, suitable for business events and conferences. This dedicated space supports various setups to meet different business needs.

Highlights

Location: one mile away from NRG Stadium

Wellness: Fitness Center & outdoor pool

Rooms: 146 newly designed guest rooms

Dining: complimentary hot breakfast

Business: meeting room accommodates up to 66 people

Shuttle: free shuttle to the Medical Center

“In my opinion, this property balances practical needs with a family-friendly atmosphere, especially convenient given its proximity to both the Texas Medical Center and NRG Stadium. I think the complimentary shuttle to area hospitals is a standout service, with guest rooms designed for longer, comfortable stays. Finally, knowing that they maintain high cleanliness standards definitely gives me confidence.”
Hotel logo
James DavidEditor-in-Chief at Cheaphotels
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Select your room type

The hotel provides a selection of rooms—doubles, family rooms, and suites—with perks like free cancellation, breakfast options, and great value deals
Specialty Room
2 persons
Air conditioning
Suite Mobility Access Roll Shower or Non-Smoking
2 persons
1 King-size bed
Shower
Air conditioning
Suite Only Hearing Accessible
2 persons
2 King Size Beds
Air conditioning
King Suite Communication Accessible
2 persons
1 King-size bed and 1 Sofa bed
Air conditioning
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Amenities & services

Real traveler stories and honest reviews—no glossy ads, just authentic feedback to guide your booking

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry
  • Dry cleaning

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Spa & Leisure

  • Outdoor swimming pool

Room features

  • Air conditioning
  • Heating
  • Tea and coffee facilities
  • Ironing facilities
  • Rollaway beds

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Location

9300 S Main Street, Houston, Texas, United States
Map view
9300 S Main Street, Houston, Texas, United States
Nearby
1000 Block South Loop
World Birding Center
560 m
Restaurants
Hank's Ice Cream Parlor
30 m
9291 Main St
Popeyes Louisiana Kitchen
1.8 km
9120 Main St
Sleepys Po-Boys
1.6 km
9591 Main St
Five Guys
1.5 km
8505 S. Main Street Unit 380
Panda Express
1.5 km
8505 Main St
Denny's
2.4 km
3332 S Loop W
Sonic Drive-In
1.8 km
8504 Main Street
Explore Houston
Explore the Local Scene
Top Attractions
Activities
Dining
Entertainment
NRG Stadium
17 minutes' walk
Home to the Houston Texans, this iconic venue hosts NFL games and epic concerts throughout the year.
Houston Zoo
50 minutes' walk
One of the country's most visited zoos, featuring diverse wildlife and engaging exhibits for all ages.
The Houston Museum of Natural Science
15 minutes' drive
A world-class museum offering fascinating exhibits, including a planetarium and a butterfly center.
Holocaust Museum Houston
10 minutes' drive
An important and moving museum dedicated to educating visitors about the Holocaust and its lessons.
Biking at Hermann Park
25 minutes' drive
Enjoy scenic bike trails and beautiful landscapes at Hermann Park, ideal for outdoor enthusiasts.
Yoga at Evelyn's Park
10 minutes' drive
Relaxing yoga sessions in a serene park setting, perfect for unwinding after a busy day.
Hank's Ice Cream Parlor
1 minute' walk
Charming parlor with homemade ice cream, offering a delightful treat just steps from the hotel.
Five Guys
18 minutes' walk
Famous for fresh burgers and fries, this casual spot is perfect for a hearty meal on the go.
NRG Arena
20 minutes' walk
A lively venue showcasing concerts and events, with a vibrant atmosphere perfect for a night out.
Jazz Education
10 minutes' walk
Enjoy live jazz performances in a cozy setting, perfect for music lovers of all ages.
Getting around town
City Centre
Houston15 min  ·  9.6 km
Airports
William P. Hobby Airport (HOU)33 min  ·  22.0 km
George Bush Intercontinental Airport - Houston (IAH)64 min  ·  42.1 km
Train
Reliant Park Station23 min  ·  1.9 km
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Check Rates
Property information and rules
Check-in
from 15:00-23:59
Check-out
until 12 pm
Guest Parking
Public parking is possible on site for free.
Internet
is available in for free.
Breakfast
The hotel Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg serves a full breakfast for free. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are not allowed.
Number of floors:
4
Number of rooms:
47
Former name
holiday inn express & suites houston s - medical ctr area, an ihg hotel
FAQs
About Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg
What are the check-in and check-out times at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Check-in is at 15:00 and check-out is by 12:00.
What is the distance from Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg to the Texas Medical Center?
The hotel is 1 km from the Texas Medical Center.
Does Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg provide free breakfast?
Complimentary breakfast is served daily at the hotel.
What amenities are available in the rooms at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Rooms include a flat-screen TV, mini-fridge, microwave, coffee maker, and private bathroom with free toiletries.
Is there a fitness center available at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Yes, the hotel has a fitness center for guests to use.
What parking options are available at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Complimentary self-parking is available on-site for guests.
How far is Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg from the Museum District?
The Museum District is located 6 km from the hotel.
What nearby dining options are available from Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Nearby restaurants include Mama's Oven (0.5 km) and Pappas Bar-B-Q (1 km).
What are the recreational amenities offered at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
The hotel features an outdoor swimming pool open from 10:00 to 22:00.
Where can business services be accessed at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
The hotel provides a business center with meeting facilities.
How far is Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg from William P. Hobby Airport?
The hotel is approximately 25 km from William P. Hobby Airport.

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